FAQ

Interested in our tests? Click below to find IVF Centers currently offering our innovative testing.

1. Patients

PGT-A (Aneuploidy):

Previously known as PGS, testing to determine if the correct chromosome number is in the embryo (explained here).

By combining copy number and genotyping data, LifeView provides the most accurate and highest resolution prediction of chromosomal abnormalities in the industry.  Fewer false positives means more embryos available for transfer.

PGT-SR (Structural Rearrangement):

Sometimes known as chromosomal PGD, testing for translocations and inversions.

LifeView PGT-SR provides more than 5 times the resolution of NGS based testing and the ability to distinguish between balanced translocation carrier and truly normal embryos for our patients.

PGT-M (Monogenic Disorders):

Sometimes known as PGD, testing for all single-gene disorders when there is a family history.

⦿ Cystic Fibrosis
⦿ Thalassemia
⦿ Huntington's disease
⦿ Our test is universal, covering all known monogenic diseases.

Copies of previous genetic testing results are required. Saliva samples from other family members may be required. Our genetic counselor and laboratory director will review your case and determine if testing is possible.

Rapid workups and broader accommodation of difficult cases means faster time to pregnancy for prospective patients.

By combining linkage-based analysis of several hundred markers with direct testing of the mutation, LifeView PGT-M provides the most convenient, cost effective, and accurate method available.

PGT-P (Polygenic Disorders):

⦿ Type 1 and Type 2 Diabetes
⦿ Breast Cancer, Testicular Cancer, Prostate Cancer, Malignant Melanoma, Basal Cell Carcinoma
⦿ Coronary Artery Disease, Heart Attack, Hypercholesterolemia, Hypertension
⦿ Schizophrenia

which-disorders-are-you-able-to-test-for

PGT-P stands for Preimplantation Genetic Testing for Polygenic disorders. Polygenic disorders are caused by variants in multiple genes.

what-is-pgt-p

Yes, the patient will be given access to download their embryo's raw genome data, in VCF file format.

https://en.wikipedia.org/wiki/Variant_Call_Format

can-i-download-my-embryo-data

2. Providers

Send us an email requesting to become a provider, at service@gpclaboratory.com.

how-do-i-send-samples-to-genomic-prediction-clinical-labs-gpcl

3. Partners

3.1

What is your position of the ethics and efficacy of PGT-A?
what-is-your-position-of-the-ethics-and-efficacy-of-pgt-a

PGT-A (Aneuploidy):

Our position on the ethics, efficacy, and science of PGT-A:


4. Press

4.1

What screening in the past has been done which is similar to PGT-P?
what-screening-in-the-past-has-been-done-which-is-similar-to-pgt-p

Our PGT-P test is entirely new and unique. No other test in history has ever offered anything like PGT-P. It is the first test to provide Polygenic Risk Scores for an embryo. PGT-P has only recently been made possible by progress on the cutting edge of scientific advance.

The American Society for Reproductive Medicine (ASRM) and Society for Assisted Reproductive Technology (SART) provides a pertinent bioethical framework which serves to guide testing of human embryos. ASRM and SART do not distinguish between monogenic and polygenic disease risk. There is a formal bioethics position on this general subject, recently updated in 2018, written by the Ethics Committee of ASRM.

A key phrase from the paper:

"PGD for adult-onset conditions is ethically justified when the condition is serious and no safe, effective interventions are available. It is ethically allowed for conditions of lesser severity or penetrance. The Committee strongly recommends that an experienced genetic counselor play a major role in counseling patients considering such procedures."

A salient example is the case of breast cancer susceptibility. Many locations in the human genome affect the polygenic trait of “Breast Cancer Risk”. The example which the bioethicists focus upon in the paper is the BRCA1 gene.

The presence of a correctly identified BRCA1 pathogenic or likely pathogenic variant increases the risk that an individual will develop cancer but the risk is not 100%. Rather, this is a single SNP, affecting a highly polygenic trait, Breast Cancer Risk.

The ASRM Ethics Committee deliberates that the benefit of reduced cancer risk is difficult to simply compare to the potential negatives induced by PGT (damage to/destruction of the embryo, incorrect genotyping resulting in transfer of an embryo with BRCA1, etc), and must be weighed in consultation with a genetic counselor.

However, PGT for BRCA1 is ultimately inferred to be ethically permissible. PGT-M for BRCA1 is practiced among members of SART, but not yet using a comprehensive, polygenic panel for the Breast Cancer Risk, PGT-P.

More generally, we adhere to the ASRM guidelines for moving innovation to practice.

4.2

Does Genomic Prediction screen purely cosmetic traits?
does-genomic-prediction-screen-purely-cosmetic-traits

No, we only provide risk scores for polygenic traits related to diseases, not for purely cosmetic traits such as hair color and eye color. Our goal is to provide improved health to IVF families.

4.3

Does Genomic Prediction Clinical Laboratory screen embryos for increased intelligence i.e. high IQ?
does-genomic-prediction-clinical-laboratory-screen-embryos-for-increased-intelligence-i-e-high-iq

No.

Creating the structures

So, as usual, I tried to make the clone as easy as possible to be copied . Just copy the element named, 'Cloneable Area' and rename it or you can copy all the elements within that class.

Both question and answer are placed within the same row and container for easier management.

Main Interactions for expand and collapse

The main interaction involved here is 'Mouse Click (Tap)' that create the animation for expand and collapse. It is targeting the main container of each row, so that user can click on anywhere within the row/container to expand or collapse an item.

Interaction for icon

Using the same interaction trigger as above, I created an animation to rotate and resize the icon to shape it from a plus to minus.

A little touch-up animation for the paragraph that reveals on expand

To make things a little livelier, I added a nice little touch up to the paragraph by creating a slide in animation from below. So, instead of being still upon expand, it will slide in from below nicely.

Additional interaction to create focus/highlight on specific item (Optional)

I added a focus/highlight effect to make the item that's on hover stands out from the rest. This helps the user to focus on the item that they are reading.

This is definitely optional. You can remove this animation from the interaction setting. It's a separate interaction from the expand/collapse.

Heading

Heading

Heading

Heading

Heading

Heading

Heading

Heading

Our mission

To accelerate the world's transition to non-being.

OUR PROJECTS

To accelerate the world's transition to non-being.

OUR FAQS

To accelerate the world's transition to non-being.

GET INVOLVED

To accelerate the world's transition to non-being.