Preimplantation Genetic Testing for Aneuploidy
Pre implantation genetic testing for aneuploidy is a genetic test performed on biopsies of embryos being used for IVF. PGT-A is formerly known as PGS, pre implantation genetic screening.
PGT-A provides information about the number of chromosomes in an embryo to help your care team select the best embryo for transfer to improve odds of a successful pregnancy outcome.
Preimplantation genetic testing of embryo health is extraordinary today.
Embryos are produced through an IVF cycle.
A small number of cells from the embryo are sent to Genomic Prediction Clinical Laboratory for analysis. Embryos are not shipped to our laboratory, we only need to examine the biopsy samples.
The team at Genomic Prediction Clinical Laboratory carefully analyzes the genetic material present within each embryo biopsy sample.
PGT-A screening is designed to detect entire chromosomes that are added or missing. The term Trisomy refers to an extra chromosome. The term Monosomy refers to a missing chromosome.
In addition to extra or missing whole chromosomes, PGT-A screening through our laboratory can detect extra or missing segments of chromosome material that are larger than 10Mb in size.
Polyploidy refers to an embryo with a whole extra set of chromosomes. Triploidy means there are three sets of chromosomes. Tetraploidy refers to anembryo with four sets of chromosomes. While polyploidy is a common cause of implantation failure and miscarriage, these types of chromosome anomalies are typically not seen following birth.