Preimplantation Genetic Testing for Aneuploidy
PGT-SR detects extra or missing chromosomal material related to a parental chromosome rearrangement. Individuals who carry a structural rearrangement have chromosomes arranged in a different order.
These rearrangements may increase the chance of fertility problems and miscarriage, and may lead to health problems following delivery.
PGT-SR is appropriate for individuals who have been identified as having a structural (chromosome) rearrangement by their physician.
A reciprocal translocation occurs when chromosome material from two different chromosomes switch places.
When two chromosomes attach together to form one larger chromosome, it is called a Robertsonian translocation. These type of chromosomes typically involve chromosomes 13, 14, 15, 21 and 22.
Inversions refer to a segment of chromosome material that is "flipped over."
In which a segment of a chromosome is missing.
In which there is an extra segment of a chromosome.
In which a segment of a chromosome is inserted.Become a patient
Genomic prediction clinical laboratory carefully reviews your genetic reports to determine the best way to proceed with testing.
The genetic counselor will review the benefits and limitations of PGT-SR testing. Parental saliva samples are collected (if possible) to aid the testing process.
Embryos are produced through an IVF cycle.
The clinic carefully takes a small sample from each embryo. A small number of cells from the embryo are sent to Genomic Prediction Clinical Laboratory for analysis. Embryos are not shipped to our laboratory, we only need to examine the biopsy samples.
The team at Genomic Prediction Clinical Laboratory carefully analyzes the genetic material present within each embryo biopsy sample.